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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECP2
All Species:
22.12
Human Site:
S70
Identified Species:
60.83
UniProt:
P51608
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51608
NP_001104262.1
486
52441
S70
E
T
S
E
G
S
G
S
A
P
A
V
P
E
A
Chimpanzee
Pan troglodytes
XP_521333
638
67833
S222
E
T
S
E
G
S
G
S
A
P
A
V
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001088566
619
66078
S203
E
T
S
E
G
S
G
S
A
P
A
V
P
E
A
Dog
Lupus familis
XP_853488
486
52281
S70
E
T
S
E
G
S
G
S
A
P
A
V
P
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D6
484
52289
S70
E
T
S
E
S
S
G
S
A
P
A
V
P
E
A
Rat
Rattus norvegicus
Q00566
492
53029
S70
E
T
S
E
S
S
G
S
A
P
A
V
P
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508704
393
42162
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081854
467
51739
E71
D
M
S
E
S
A
E
E
N
L
A
V
P
E
S
Zebra Danio
Brachydanio rerio
NP_997901
524
57133
A79
P
I
D
P
E
V
G
A
A
L
S
A
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.8
78.1
96.5
N.A.
95.2
94.3
N.A.
65.2
N.A.
65.6
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.1
78.5
97.5
N.A.
96.5
95.9
N.A.
71.1
N.A.
75
62.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
78
0
78
12
0
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
67
0
0
78
12
0
12
12
0
0
0
0
0
89
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
45
0
78
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
12
0
0
12
0
0
0
0
0
67
0
0
89
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
78
0
34
67
0
67
0
0
12
0
0
0
23
% S
% Thr:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
78
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _